Dror Berel

Independent Consultant / Freelancer

R Pharmaverse Teal Shiny

R programmer focused on clinical reporting and Teal dashboards for pharma teams.

dror.berel@gmail.com

🚀 Rapid Deployment & Implementation

From Zero to Production in Weeks - Not Months

  • Deploy fully validated Teal dashboards for Phase I-IV clinical trials with industry-standard modules
  • Implement out-of-the-box safety tables (AE summaries, lab trends, exposure analysis) compliant with ICH-E3 guidelines
  • Configure efficacy endpoints modules (time-to-event, binary outcomes, longitudinal analyses) for regulatory submissions
  • Integrate CDISC-compliant datasets (SDTM, ADaM) with automated validation and quality checks
  • Adapt Teal framework to non-standard data sources: real-world evidence, patient registries, observational studies
  • Deliver GxP-validated environments with complete Installation/Operational Qualification documentation

🎨 Custom Module Development & Unique Visualizations

Bring Your Vision to Life - Bespoke Clinical Visualizations

  • Design custom patient journey timelines showing treatment progression, dose modifications, and clinical events
  • Build advanced waterfall plots with RECIST criteria, biomarker overlays, and response annotations Create interactive swimmer plots displaying multi-therapy timelines, adverse events, and disease milestones
  • Develop proprietary in-house modules tailored to your therapeutic area (oncology, cardiology, rare diseases)
  • Package reusable module libraries for standardized company-wide reporting frameworks
  • Implement branded dashboards matching corporate design guidelines and color schemes
  • Deliver fully documented and validated custom modules ready for regulatory inspection

⚡ Interactive Drill-Down & JavaScript-Powered Analytics

Click, Explore, Discover - Next-Generation Clinical Intelligenc

  • Build multi-level drill-down systems: summary → cohort → individual patient with seamless navigation Embed JavaScript-powered visualizations using Plotly, D3.js, Highcharts for publication-quality graphics
  • Implement clickable adverse event hierarchies: SOC → HLGT → PT with instant patient listings
  • Create interactive patient profiles with synchronized timelines, lab values, and treatment history Deploy real-time filtering and brushing across linked visualizations for exploratory analysis
  • Add custom tooltips and annotations with patient-level details accessible on hover/click 
  • Enable dynamic report generation capturing user interactions and filter states for reproducibility

💼 Value Proposition

Accelerate Insights, Reduce Timelines, Ensure Compliance

  • Speed to insights: Reduce dashboard development time by 60-80% vs. custom Shiny builds - Regulatory-ready: Built-in validation framework meeting FDA/EMA electronic submission requirements
  • Cost-effective: Leverage open-source pharmaverse ecosystem with enterprise support
  • Scalable: Modular architecture grows from pilot studies to multi-study portfolios User empowerment: Enable clinical teams to explore data without programming knowledge
  • Future-proof: Active community support and continuous updates from pharmaverse contributors

🎯 Industries & Use Cases

  • Pharmaceutical companies: Phase I-IV trial monitoring and regulatory submissions
  • Biotech startups: Rapid dashboard deployment for investor presentations and data reviews
  • CROs: Standardized reporting platforms across multiple client trials
  • Academic medical centers: Investigator-initiated trials and real-world evidence studies
  • Regulatory agencies: Interactive review tools for submission assessment

📊 Technical Differentiators

  • Full-stack expertise: R/Shiny + JavaScript + validation + CDISC standards End-to-end delivery: Requirements gathering → development → validation → deployment → training
  • Proven methodology: Agile development with 2-week sprint cycles and continuous stakeholder feedback
  • Knowledge transfer: Comprehensive documentation and team training for sustainable maintenance Ongoing support: Post-deployment optimization, troubleshooting, and feature enhancements

Writing

  • Teal App Development in Pharmaverse — Practical patterns for Teal app development. Read
  • R & Shiny Notes — Applied tips and examples from client work. Read

App Demos

  • Exploratory Dashboard — Cohort exploration and drill‑down views. Open
  • Safety Dashboard — AE/SAE review with interactive filters. Open
  • Efficacy Dashboard — Outcome views and subgroup comparisons. Open
  • Patient Profile — Patient‑level timelines and summary panels. Open

Open Source

  • Bioc2mlr — Legacy R code example. Code
  • JDRFCAV — Legacy R code example. Code

Case Studies

Teal Dashboard Build (from 0 to 20 Modules in less than a month)

Situation: Needed a full Teal dashboard built rapidly from scratch.

  • Work: Implemented Teal dashboard architecture and delivered 20 modules
  • Impact: Delivered in under one month

Teal Framework Migration

Situation: Existing in‑house visualizations and reports needed to move to Teal.

  • Work: Re‑implemented visualizations and reports within Teal with validated components
  • Impact: Standardized delivery and validation across modules

About

I’m a one-stop-shop consultancy focused on validated clinical analytics. I work directly with teams to design, build, and maintain R‑based reporting and Teal dashboards that meet regulatory and quality expectations.

Contact

If you have a project in mind, send a brief note with your goals, timeline, and constraints. I’ll follow up to discuss how I can help.

dror.berel@gmail.com

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